01. Hypothesis
We frame testable questions, map assumptions, and define failure criteria before analysis begins.
Independent Nonprofit Computational Research Lab
Advancing ScienceThrough Human–AIRigorous Collaboration
Santaros Labs studies how scientists and AI can reason, write code, analyze evidence, and build knowledge together—without losing rigor, provenance, or human judgment.
OUR FOUNDATION
Independent Nonprofit LabPI-Accountable GovernanceNatural Sciences & ComputingReproducible WorkflowsOpen ProtocolsResearch Partnerships
MISSION
Make AI-Assisted Science More Reliable
Santaros Labs is a nonprofit research organization focused on the methods of AI-assisted science. We study how evidence is gathered, transformed, checked, and communicated across the full research workflow.
Our Research Loop
02. Computation
We build traceable AI-assisted workflows for literature, code, modeling, and data analysis.
03. Validation
We test reliability with blinded checks, replication, audit trails, and clearly reported limitations.
Core Research Questions
AI for Scientific Reasoning
Testing where AI expands hypothesis generation—and where it introduces confident error.
Reproducible Analysis
Designing research workflows that another scientist can inspect, rerun, and challenge.
Team-Scale Research
Studying shared AI workspaces, handoffs, provenance, and collective scientific judgment.
Evidence Integrity
Measuring citation fidelity, uncertainty calibration, contradiction handling, and error detection.
EVIDENCE INTEGRITY
Evidence That Can Survive Scrutiny
We separate proposed work from completed work, publish methods before outcomes when feasible, and preserve the chain from source material to code, result, interpretation, and limitation.
Preregistration-ready protocols
Reproducible computational workflows
Mixed-method evaluation
Transparent limitations
Cross-disciplinary collaboration
SUPPORT OUR WORK
Support Research for Trustworthy Scientific AI
Santaros Labs welcomes grants, philanthropic support, compute credits, data partnerships, and scientific collaborators for reproducibility and human–AI research.
Support enables:
- Protocol development
- Research staff
- Secure compute
- Open-source tooling
- Replication studies
PARTNER WITH US
Build More Reliable Scientific Workflows
Santaros Labs welcomes principal investigators, research groups, nonprofit institutes, funders, and technical partners who want AI-assisted science to be inspectable, reproducible, and useful.